Cryptic crossword clue
This French beer damaged and completely upset portions of the brain 9

The most common and most likely answer to this crossword clue is the 9 letter word CEREBELLA

C
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B
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Buddy explains!

The straight part
We know that "portions of the brain" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case portions of the brain = cerebella.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CEREBELLA mean?

CEREBELLA noun
  1. Part of the hindbrain in vertebrates. In humans it lies between the brainstem and the cerebrum. It plays an important role in sensory perception, motor output, balance and posture.

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