Cryptic crossword clue
This great novel is one of love that reigns 7

The most common and most likely answer to this crossword clue is the 7 letter word ANAGRAM

I've seen this crossword clue in Financial Times
A
N
A
G
R
A
M


Buddy explains!

The straight part
We know that "one" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one = anagram.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANAGRAM mean?

ANAGRAM noun
  1. (of words) A word or phrase that is created by rearranging the letters of another word or phrase.
ANAGRAM verb
  1. To form anagrams.

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