The most common and most likely answer to this crossword clue is the 3 plus 6 plus 4 letter word TWO LITTLE BOYS
I've seen this crossword clue in The Guardian
T
W
O
L
I
T
T
L
E
B
O
Y
S
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.