Cryptic crossword clue
Three bits missing from end of fifth book or two very small bits? 8

The most common and most likely answer to this crossword clue is the 8 letter word DEUTERON

I've seen this crossword clue in Financial Times
D
E
U
T
E
R
O
N


Buddy explains!

The straight part
We know that "two very small bits" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case two very small bits = deuteron.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEUTERON mean?

DEUTERON noun
  1. The atomic nucleus of a deuterium atom, consisting of a proton and a neutron

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