Cryptic crossword clue
Throttling, twisting gag in last turn 13

The most common and most likely answer to this crossword clue is the 13 letter word STRANGULATING

I've seen this crossword clue in The Daily Telegraph
S
T
R
A
N
G
U
L
A
T
I
N
G

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STRANGULATING mean?

STRANGULATING verb
  1. To stop flow through a vessel.
  2. To strangle.

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