Cryptic crossword clue
Throw into confusion with failure to capture gunmen in the centre of Honolulu 10

The most common and most likely answer to this crossword clue is the 10 letter word DEMORALISE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Throw into confusion" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case throw into confusion = demoralise.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEMORALISE mean?

DEMORALISE verb
  1. To destroy the morale of; to dishearten.

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