Cryptic crossword clue
Throw off course queen in foreign parliament 6

The most common and most likely answer to this crossword clue is the 6 letter word DERAIL

I've seen this crossword clue in The Daily Telegraph
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Buddy explains!

The straight part
We know that "Throw off" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case throw off = derail.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DERAIL mean?

DERAIL noun
  1. A device placed on railway tracks causing a train to derail.
  2. An instance of diverting a conversation or debate from its original topic.
DERAIL verb
  1. To cause to come off the tracks.
  2. To come off the tracks.
  3. To deviate from the previous course or direction.
  4. To cause to deviate from a set course or direction; derange.

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