The most common and most likely answer to this crossword clue is the 10 letter word GESUNDHEIT
I've seen this crossword clue in The Guardian
G
E
S
U
N
D
H
E
I
T
Buddy explains!
The straight part
We know that "as lesser explosion acknowledged in Berlin" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case as lesser explosion acknowledged in berlin = gesundheit.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GESUNDHEIT mean?
GESUNDHEIT interjection- Said to someone who has just sneezed.
- Said as a response to someone who said something difficult or convoluted.