The most common and most likely answer to this crossword clue is the 8 letter word NIHILITY
N
I
H
I
L
I
T
Y
Buddy explains!
The straight part
We know that "absolutely nothing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case absolutely nothing = nihility.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does NIHILITY mean?
NIHILITY noun- Nothingness, nullity.