Cryptic crossword clue
Tiresome Irish girl can start to grate 10

The most common and most likely answer to this crossword clue is the 10 letter word IRRITATING

I've seen this crossword clue in The Guardian
I
R
R
I
T
A
T
I
N
G

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IRRITATING mean?

IRRITATING verb
  1. To provoke impatience, anger, or displeasure in.
  2. To cause or induce displeasure or irritation.
  3. To induce pain in (all or part of a body or organism).
  4. To render null and void.
IRRITATING adjective
  1. Causing irritation, annoyance or pain.
  2. Stimulating or exciting a response.

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