The most common and most likely answer to this crossword clue is the 10 letter word RUTHERFORD
I've seen this crossword clue in The Times
R
U
T
H
E
R
F
O
R
D
More clues leading to the result RUTHERFORD
- Pity old queen having to face cross physicist
- Titled actress has boring routine with her car
- Scientist woman's cross with dull routine
- Physicist badly hurt internally very cross
- Scientist’s lady’s cross, oppressed by dull routine
- Physicist’s tedious routine with woman’s car
- He followed Ulysses further astray, got nothing right, and died
Buddy explains!
The straight part
We know that "Titled actress" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case titled actress = rutherford.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.