Cryptic crossword clue
Toiling away at first, reproducing artwork 8

The most common and most likely answer to this crossword clue is the 8 letter word INTAGLIO

I've seen this crossword clue in Financial Times
I
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Buddy explains!

The straight part
We know that "artwork" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case artwork = intaglio.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INTAGLIO mean?

INTAGLIO noun
  1. A design or piece of art which is engraved or etched into something.
  2. Any printing method in which the ink is laid upon the sunken parts of the printing form.
INTAGLIO verb
  1. To engrave or etch using intaglio.

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