Cryptic crossword clue
Took a zigzag course in dirty old Salem 8

The most common and most likely answer to this crossword clue is the 8 letter word SLALOMED

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Buddy explains!

The straight part
We know that "Took a zigzag course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case took a zigzag course = slalomed.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SLALOMED mean?

SLALOMED verb
  1. To race in a slalom.
  2. To move in a slalom-like manner.

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