Cryptic crossword clue
Top job in transformed Irish depot 10

The most common and most likely answer to this crossword clue is the 10 letter word EDITORSHIP

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Top job" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case top job = editorship.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EDITORSHIP mean?

EDITORSHIP noun
  1. The position or job of being an editor

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