The most common and most likely answer to this crossword clue is the 8 letter word INVERTED
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Buddy explains!
The straight part
We know that "Topsy-turvy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case topsy-turvy = inverted.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does INVERTED mean?
INVERTED verb- To turn (something) upside down or inside out; to place in a contrary order or direction.
- To move (the root note of a chord) up or down an octave, resulting in a change in pitch.
- To undergo inversion, as sugar.
- To divert; to convert to a wrong use.
- To turn (the foot) inwards.
- Having the order or direction changed; for example turned upside down, reversed or in any other way opposite or contrary.
- Homosexual.
- (of a chord) Having the lowest note transposed an octave higher.
- (of sugar) Having its polarization changed by hydrolysis; see invert sugar.