The most common and most likely answer to this crossword clue is the 10 letter word UPSETTINGÂ
I've seen this crossword clue in The Guardian
U
P
S
E
T
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Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does UPSETTINGÂ mean?
UPSETTINGÂ verb- To make (a person) angry, distressed, or unhappy.
- To disturb, disrupt or adversely alter (something).
- To tip or overturn (something).
- To defeat unexpectedly.
- To be upset or knocked over.
- To set up; to put upright.
- To thicken and shorten, as a heated piece of iron, by hammering on the end.
- To shorten (a tire) in the process of resetting, originally by cutting it and hammering on the ends.
- The action of the verb upset.
- Causing upset; distressing.
- Conceited; presumptuous.