The most common and most likely answer to this crossword clue is the 6 letter word RUINED
I've seen this crossword clue in The Guardian
R
U
I
N
E
D
More clues leading to the result RUINED
- Bankrupt regretted keeping fashionable
- Regretted being without home, broke
- Game one lout wrecked
- Bankrupt, one enters “under review”
- Ancient letter about Independence Day’s damaged
- Bust bouncing about in red underwear, initially
- Spoiled rotten
- One overturning animal’s home after game’s shot
- Trashed uniform adopted by leftie
- Knocked down in rude dancing
Buddy explains!

The straight part
We know that "Trashed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case trashed = ruined.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RUINED mean?
RUINED verb- To cause the fiscal ruin of.
- To destroy or make something no longer usable.
- To cause severe financial loss to; to bankrupt or drive out of business.
- To upset or overturn the plans or progress of, or to have a disastrous effect on something.
- To make something less enjoyable or likeable.
- To reveal the ending of (a story); to spoil.
- To fall into a state of decay.
- To seduce or debauch, and thus harm the social standing of.
- Incapacitated by drugs or alcohol