Cryptic crossword clue
Treat with contempt as showing signs of exhaustion 3,4

The most common and most likely answer to this crossword clue is the 3 plus 4 letter word RUN DOWN

I've seen this crossword clue in The Daily Telegraph
R
U
N
D
O
W
N


Buddy explains!

The straight part
We know that "Treat with contempt/showing signs of exhaustion" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case treat with contempt/showing signs of exhaustion = run down.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RUN DOWN mean?

RUN DOWN adjective
  1. (of a person) Tired and exhausted.
  2. (of a place) Decrepit.
  3. (of a clockwork mechanism) Having the spring unwound.

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