Cryptic crossword clue
Treated invalid aunt— exhausted, sick person a recluse

The most common and most likely answer to this crossword clue is the 14 letter word VALETUDINARIAN

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Buddy explains!

The straight part
We know that "sick person" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sick person = valetudinarian.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VALETUDINARIAN mean?

VALETUDINARIAN noun
  1. A person in poor health or sickly, especially one who is constantly obsessed with their state of health
VALETUDINARIAN adjective
  1. Sickly, infirm, of ailing health
  2. Being overly worried about one's health

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