Cryptic crossword clue
Treating as invalid approve keeping, having unhealthy complexion, at home 11

The most common and most likely answer to this crossword clue is the 11 letter word DISALLOWING

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Buddy explains!

The straight part
We know that "Treating as invalid" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case treating as invalid = disallowing.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISALLOWING mean?

DISALLOWING verb
  1. To refuse to allow
  2. To reject as invalid, untrue, or improper

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