The most common and most likely answer to this crossword clue is the 5 plus 5 letter word FIRST WORLD
I've seen this crossword clue in The Guardian
F
I
R
S
T
W
O
R
L
D
Buddy explains!
The straight part
We know that "leading industrial nations" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case leading industrial nations = first world.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.