Cryptic crossword clue
Trendy grub with pickled eel bits is hard to take in 12

The most common and most likely answer to this crossword clue is the 12 letter word INDIGESTIBLE

I've seen this crossword clue in The Times
I
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D
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Buddy explains!

The straight part
We know that "hard to take in" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hard to take in = indigestible.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INDIGESTIBLE mean?

INDIGESTIBLE noun
  1. Anything that is difficult to digest.
INDIGESTIBLE adjective
  1. Difficult or impossible to digest.
  2. (by extension) Difficult to accept; unpalatable.

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