The most common and most likely answer to this crossword clue is the 12 letter word TESTOSTERONE
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More clues leading to the result TESTOSTERONE
Buddy explains!
The straight part
We know that "It might make a man of you" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it might make a man of you = testosterone.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TESTOSTERONE mean?
TESTOSTERONE noun- Steroid hormone produced primarily in the testes of the male; it is responsible for the development of secondary sex characteristics in the male.
- Manly behavior, often of an aggressive or foolishly reckless nature.