Cryptic crossword clue
Tricks of one who proved Fermat’s last theorem 5

The most common and most likely answer to this crossword clue is the 5 letter word WILES

I've seen this crossword clue in The Guardian
W
I
L
E
S

Buddy explains!

The straight part
We know that "Tricks/one who proved Fermat’s last theorem" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case tricks/one who proved fermat’s last theorem = wiles.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WILES mean?

WILES noun
  1. (usually in the plural) A trick or stratagem practiced for ensnaring or deception; a sly, insidious artifice

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