Cryptic crossword clue
Tricky situation – I caught a beastly disease 7

The most common and most likely answer to this crossword clue is the 7 letter word SCRAPIE

S
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Buddy explains!

The straight part
We know that "a beastly disease" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a beastly disease = scrapie.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SCRAPIE mean?

SCRAPIE noun
  1. A degenerative prion disease of sheep and goats that attacks the central nervous system.

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