The most common and most likely answer to this crossword clue is the 3 plus 5 plus 2 plus 3 letter word THE DEVIL TO PAY
I've seen this crossword clue in The Daily Telegraph
T
H
E
D
E
V
I
L
T
O
P
A
Y
Buddy explains!
The straight part
We know that "Trouble" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case trouble = the devil to pay.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.