Cryptic crossword clue
Trousers that come sizes 8, 12 and 16? 4,5

The most common and most likely answer to this crossword clue is the 4 plus 5 letter word PLUS FOURS

P
L
U
S
F
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Buddy explains!

The straight part
We know that "Trousers" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case trousers = plus fours.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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