Cryptic crossword clue
True about first half of semi being close again 6

The most common and most likely answer to this crossword clue is the 6 letter word RESEAL

R
E
S
E
A
L


Buddy explains!

The straight part
We know that "close again" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case close again = reseal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RESEAL mean?

RESEAL verb
  1. To seal (something) again (in any sense of "apply a seal to").

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