Cryptic crossword clue
True comedians performing in factual TV programmes

The most common and most likely answer to this crossword clue is the 13 letter word DOCUMENTARIES

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "factual TV programmes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case factual tv programmes = documentaries.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DOCUMENTARIES mean?

DOCUMENTARIES noun
  1. A film, TV program, publication etc. which presents a social, political, scientific or historical subject in a factual or informative manner.

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