Cryptic crossword clue
Turn against at all times 4

The most common and most likely answer to this crossword clue is the 4 letter word VEER

I've seen this crossword clue in The Guardian
V
E
E
R


Buddy explains!

The straight part
We know that "Turn/Turn" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case turn/turn = veer.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VEER mean?

VEER verb
  1. To let out (a sail-line), to allow (a sheet) to run out.
VEER noun
  1. A turn or swerve; an instance of veering.
VEER verb
  1. To change direction or course suddenly; to swerve.
  2. (of the wind) To shift in a clockwise direction (if in the Northern Hemisphere, or in a counterclockwise direction if in the Southern Hemisphere).
  3. (of the wind) To shift aft.
  4. To change direction into the wind; to wear ship.
  5. To turn.

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