Cryptic crossword clue
Twice frustrate evidence of PO 11

The most common and most likely answer to this crossword clue is the 11 letter word COUNTERFOIL

I've seen this crossword clue in Financial Times
C
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Buddy explains!

The straight part
We know that "evidence of PO" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case evidence of po = counterfoil.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COUNTERFOIL mean?

COUNTERFOIL noun
  1. The part of a cheque that is retained in the chequebook as a record; a stub

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