Cryptic crossword clue
Twickenham to some, top news, maybe? 12

The most common and most likely answer to this crossword clue is the 12 letter word HEADQUARTERS

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Buddy explains!

The straight part
We know that "Twickenham to some" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case twickenham to some = headquarters.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HEADQUARTERS mean?

HEADQUARTERS noun
  1. The military installation from which troops are commanded and orders are issued; the military unit consisting of a commander and his support staff.
  2. The center of an organization's operations or administration.
  3. A place of concentrated activity or influence.

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