Cryptic crossword clue
Twinkling finale for virtuoso part in duet 7

The most common and most likely answer to this crossword clue is the 7 letter word SECONDO

I've seen this crossword clue in The Guardian
S
E
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Buddy explains!

The straight part
We know that "part in duet" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case part in duet = secondo.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SECONDO mean?

SECONDO noun
  1. The second part in a concerted piece.

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