The most common and most likely answer to this crossword clue is the 9 letter word MISSHAPEN
I've seen this crossword clue in The Times
M
I
S
S
H
A
P
E
N
More clues leading to the result MISSHAPEN
- Twisted young woman beginning to harass a writer
- Teacher by chance losing some power gets squashed
- Girl has cut quill crooked
- Deformed young woman almost slept with writer
- Aberrant, erratic emphasis placed on noun
- Skip and arise half-heartedly, getting twisted
- Ugly girl, female bird catching old man rising
- Distorted spin has me confused
Buddy explains!

The straight part
We know that "Twisted" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case twisted = misshapen.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does MISSHAPEN mean?
MISSHAPEN adjective- Having a bad, ugly or awkward shape; deformed; malformed.
- Morally or intellectually warped.