The most common and most likely answer to this crossword clue is the 6 letter word JACOBI
I've seen this crossword clue in Financial Times
J
A
C
O
B
I
More clues leading to the result JACOBI
- Thespian, one supporting someone with a ladder
- Knighted actor’s dodgy CIA job
- Actor producing short flag beside sash
- Actor‘s business and current account’s broken into
- Swan in prison, no finale for Shakespearean actor
- Two-thirds of James II’s supporters, according to mathematician
- Seventh note put out by one seeking restoration for actor
- Work involving short performance with one famous actor
Buddy explains!

The straight part
We know that "mathematician" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mathematician = jacobi.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.