The most common and most likely answer to this crossword clue is the 7 letter word CLEANUP
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More clues leading to the result CLEANUP
Buddy explains!
The straight part
We know that "a great profit" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a great profit = cleanup.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CLEANUP mean?
CLEANUP noun- The act of cleaning or tidying something.
- Fourth in the batting order; a cleanup hitter.