Cryptic crossword clue
Uncle slowing down Amercian Prof who’s retired 8

The most common and most likely answer to this crossword clue is the 8 letter word EMERITUS

I've seen this crossword clue in Financial Times
E
M
E
R
I
T
U
S


Buddy explains!

The straight part
We know that "Prof who’s retired" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case prof who’s retired = emeritus.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EMERITUS mean?

EMERITUS noun
  1. A person retired in this sense.
EMERITUS adjective
  1. Retired, but retaining an honorific version of a previous title.

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