Cryptic crossword clue
Unconventional folks treated snakebite with amputation 8

The most common and most likely answer to this crossword clue is the 8 letter word BEATNIKS

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The straight part
We know that "Unconventional folks" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case unconventional folks = beatniks.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BEATNIKS mean?

BEATNIKS noun
  1. A person who dresses in a manner that is not socially acceptable and therewith is supposed to reject conventional norms of thought and behavior; nonconformist in dress and behavior
  2. A person associated with the Beat Generation of the 1950s and 1960s or its style.

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