Cryptic crossword clue
Uneasy with this hormone, rep produces progesterone 9

The most common and most likely answer to this crossword clue is the 9 letter word OESTROGEN

I've seen this crossword clue in The Guardian
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What does OESTROGEN mean?

OESTROGEN noun
  1. Any of a group of steroids that are secreted by the ovaries and function as female sex hormones.

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