The most common and most likely answer to this crossword clue is the 3 plus 2 plus 3 letter word ACT OF GOD
I've seen this crossword clue in The Daily Telegraph
A
C
T
O
F
G
O
D
More clues leading to the result ACT OF GOD
- Ultimately, eating cat food could spell disaster!
- Freak accident of cat with dog barking
- Maybe making light of natural disaster
- Creation, say, of sudden and natural occurrence
- Unforeseen event caused by source of germs in recooked cat food
- Terrible catastrophe... food is distributed outside entrance to Gurudwara by Bill
- Isis' role possibly in a catastrophe
- Terrible event, perhaps — in fact good, strangely
- Unavoidable disaster, in fact good, perversely
- German tucks into cat food mistakenly – a disaster, naturally
Buddy explains!

The straight part
We know that "Unforeseen event" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case unforeseen event = act of god.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.