The most common and most likely answer to this crossword clue is the 3 letter word BIZ
B
I
Z
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BIZ mean?
BIZ noun- Business.