Cryptic crossword clue
Unknown person sneaking in slyly, drylyOH, OH! 8

The most common and most likely answer to this crossword clue is the 8 letter word HYDROXYL

H
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O
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Buddy explains!

The straight part
We know that "OH" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case oh = hydroxyl.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HYDROXYL mean?

HYDROXYL noun
  1. A univalent radical or functional group (–OH) in organic chemistry; present in alcohols, phenols, carboxylic acids and certain other classes of compounds.

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