Cryptic crossword clue
Unknown to babble at length about one tiny item charged 10

The most common and most likely answer to this crossword clue is the 10 letter word ZWITTERION

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Buddy explains!

The straight part
We know that "tiny item charged" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case tiny item charged = zwitterion.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ZWITTERION mean?

ZWITTERION noun
  1. A molecule, such as an amino acid, that carries both a positive and a negative charge.

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