Cryptic crossword clue
Unnatural condition of dictionary with letter M before A

The most common and most likely answer to this crossword clue is the 6 letter word OEDEMA

I've seen this crossword clue in The Guardian
O
E
D
E
M
A

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The straight part
We know that "Unnatural condition" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case unnatural condition = oedema.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OEDEMA mean?

OEDEMA noun
  1. An excessive accumulation of serum in tissue spaces or a body cavity
  2. A similar swelling in plants caused by excessive accumulation of water

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