Cryptic crossword clue
Unplanned confrontation with American during depression 12

The most common and most likely answer to this crossword clue is the 12 letter word COINCIDENTAL

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "Unplanned" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case unplanned = coincidental.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COINCIDENTAL mean?

COINCIDENTAL adjective
  1. Occurring as or resulting from coincidence.
  2. Happening or existing at the same time.

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