Cryptic crossword clue
Unwanted growth in cold, tossed macaroni 9

The most common and most likely answer to this crossword clue is the 9 letter word CARCINOMA

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Buddy explains!

The straight part
We know that "Unwanted growth" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case unwanted growth = carcinoma.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CARCINOMA mean?

CARCINOMA noun
  1. An invasive malignant tumor derived from epithelial tissue that tends to metastasize to other areas of the body.

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