Cryptic crossword clue
Unwilling to be sick 10

The most common and most likely answer to this crossword clue is the 10 letter word INDISPOSED

I've seen this crossword clue in The Daily Telegraph
I
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D
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Buddy explains!

The straight part
We know that "Unwilling/sick" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case unwilling/sick = indisposed.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INDISPOSED mean?

INDISPOSED adjective
  1. Mildly ill.
  2. Not disposed, predisposed, or inclined; unwilling.
  3. Not yet ready (especially with regard to receiving a visitor) because not yet arranged into a state of readiness (i.e., not disposed); (especially, more specifically):

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