Cryptic crossword clue
US actor’s gown oddly tried on by Republican 6,2,4

The most common and most likely answer to this crossword clue is the 6 plus 2 plus 4 letter word ROBERT DE NIRO

I've seen this crossword clue in Financial Times
R
O
B
E
R
T
D
E
N
I
R
O

Buddy explains!

The straight part
We know that "US actor" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case us actor = robert de niro.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

Latest crossword clues with full explanations