Cryptic crossword clue
US novelist Bill's taken ill, is back 7

The most common and most likely answer to this crossword clue is the 7 letter word ELLISON

E
L
L
I
S
O
N

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The straight part
We know that "US novelist" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case us novelist = ellison.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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