Cryptic crossword clue
Use abusive language against English organ that’s taken up 6

The most common and most likely answer to this crossword clue is the 6 letter word REVILE

I've seen this crossword clue in The Daily Telegraph
R
E
V
I
L
E

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REVILE mean?

REVILE noun
  1. Reproach; reviling
REVILE verb
  1. To attack (someone) with abusive language.

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